Neoplastic disease and thyrotoxicosis

Bone disease in thyrotoxicosis

Thyrotoxicosis, a clinical syndrome characterized by manifestations of excess thyroid hormone, is one of the commonly-recognised conditions of the thyroid gland. Thyrotoxicosis causes acceleration of bone remodelling and though it is one of the known risk factors for osteoporosis, the metabolic effects of thyroxine on bone are not well discussed. Studies show that thyroid hormones have effects ...

Graves’ Disease and the Manifestations of Thyrotoxicosis

Graves' disease includes thyrotoxicosis, goiter, exophthalmos, and pretibial myxedema when fully expressed, but can occur with one or more of these features. Graves' disease is a disease of "autoimmunity", but the final cause of autoimmunity remains unclear. A strong hereditary tendency is present. Inheritance of HLA antigens DR3, DQ 2, and DQA1*0501 predispose to Graves' disease. The abnormal ...

Co-existence of Addison's disease and thyrotoxicosis.

Addison's disease and thyrotoxicosis presenting simultaneously.

The simultaneous presentation of two endocrinological diseases is uncommon. A case is discussed in which Addison's disease and thyrotoxicosis were discovered in an individual following presentation as an emergency neurological problem.

Neoplastic and non-neoplastic ovarian disease in Zimbabwean women.

Disease of the ovary are a significant cause of morbidity and mortality amongst Zimbabwean women. There is however, scanty data regarding the types and extent of these conditions. A retrospective review of histologically diagnosed ovarian disease was carried out in order to determine the types, prevalence and age distribution of ovarian pathology seen in Harare over a 22 month period. Pathologi...